Item Type | Name |
Academic Article
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Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.
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Academic Article
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A genetic screen for candidate tumor suppressors identifies REST.
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Concept
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Repressor Proteins
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Academic Article
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Evolutionary relationships and functional conservation among vertebrate Max-associated proteins: the zebra fish homolog of Mxi1.
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Academic Article
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Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1.
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Academic Article
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Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein.
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Academic Article
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The LKB1 tumor suppressor negatively regulates mTOR signaling.
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Academic Article
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HDAC2 negatively regulates memory formation and synaptic plasticity.
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Academic Article
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Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2.
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Academic Article
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Distinct requirements for Sin3a in perinatal male gonocytes and differentiating spermatogonia.
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Academic Article
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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.
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Academic Article
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Overexpression of Mad transcription factor inhibits proliferation of cultured human hepatocellular carcinoma cells along with tumor formation in immunodeficient animals.
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Academic Article
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Hepatocyte transplantation improves survival in mice with liver toxicity induced by hepatic overexpression of Mad1 transcription factor.
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Academic Article
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mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells.
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Academic Article
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Cancer: crime and punishment.
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Academic Article
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Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation.
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Academic Article
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Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma.
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Academic Article
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Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells.
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Academic Article
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Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.
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Academic Article
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Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1.
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Academic Article
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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression.
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Academic Article
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Functional interactions among members of the Myc superfamily and potential relevance to cutaneous growth and development.
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Academic Article
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Repression by the Mad(Mxi1)-Sin3 complex.
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Academic Article
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Gene-target recognition among members of the myc superfamily and implications for oncogenesis.
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Academic Article
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Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
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Academic Article
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mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival.
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Academic Article
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Haploinsufficiency of the mSds3 chromatin regulator promotes chromosomal instability and cancer only upon complete neutralization of p53.
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Academic Article
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STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation.
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Academic Article
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An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3.
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Academic Article
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A biochemical and biological analysis of Myc superfamily interactions.
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Academic Article
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Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation.
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